Investigating a new neural pathway that controls feeding behavior
A novel MC4R neural pathway in feeding
This study is looking at how certain brain cells control eating and weight, with the hope of finding new ways to treat obesity that work better and have fewer side effects, so it could help people struggling with their weight.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11091417 on NIH RePORTER |
What this research studies
This research focuses on understanding the neural pathways that regulate body weight and feeding behavior, specifically through the melanocortin receptors in the brain. By using advanced techniques like optogenetics, the study aims to explore how specific neurons in the paraventricular hypothalamus influence feeding through their connections to other brain regions. The goal is to identify potential therapeutic targets for obesity treatment that minimize side effects and improve efficacy. Patients may benefit from insights that could lead to new obesity treatments based on these neural mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals struggling with obesity or related metabolic disorders.
Not a fit: Patients who are not affected by obesity or do not have related metabolic conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and targeted therapies for obesity with fewer side effects.
How similar studies have performed: Other research has shown promise in targeting neural pathways for obesity treatment, but this specific approach is novel and untested.
Where this research is happening
Houston, United States
- University of Texas Hlth Sci Ctr Houston — Houston, United States (Active)
Researchers
- Principal investigator: Tong, Qingchun — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Tong, Qingchun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.