Investigating a new microprotein's role in healing wounds and its connection to cancer
The Roles of a Novel Microprotein in Wound Healing and Cancer
This study is looking at a tiny protein called TINCR-MP to see how it helps with healing wounds and how it changes in cancer, with the hope of finding new ways to treat both conditions that could help patients like you.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-10892237 on NIH RePORTER |
What this research studies
This research focuses on understanding how a newly discovered microprotein, TINCR-MP, influences wound healing processes and how its function is altered in cancer. By examining the pathways that regulate cell proliferation and migration, the study aims to identify potential therapeutic targets for cancer treatment. The research utilizes advanced techniques, including CRISPR-based screens, to explore the microprotein's interactions and effects on skin models. Patients may benefit from insights that could lead to innovative treatments for both wound healing and cancer.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with chronic wounds or those diagnosed with cancer, particularly breast cancer.
Not a fit: Patients with acute wounds or those not affected by cancer may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for improving wound healing and treating cancer.
How similar studies have performed: Other research has shown promise in targeting microproteins for therapeutic purposes, suggesting a potential for success in this novel approach.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Martinez, Thomas Farid — University of California-Irvine
- Study coordinator: Martinez, Thomas Farid
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.