Investigating a new medication for treating Alcohol Use Disorder
A pharmacogenetic human laboratory investigation of brexpiprazole in Alcohol Use Disorder
['FUNDING_R01'] · UNIVERSITY OF COLORADO DENVER · NIH-10678836
This study is looking at how well a new medication called brexpiprazole works for people with Alcohol Use Disorder, and it will also check if certain genes can help predict how well someone will respond to the treatment, all to help create more personalized care for those struggling with alcohol use.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF COLORADO DENVER (nih funded) |
| Locations | 1 site (Aurora, UNITED STATES) |
| Trial ID | NIH-10678836 on ClinicalTrials.gov |
What this research studies
This research explores the effectiveness of brexpiprazole, a novel medication, in treating Alcohol Use Disorder (AUD) by examining how genetic factors influence individual responses to the drug. The study aims to identify specific genetic markers that may predict how well patients will respond to brexpiprazole, thereby advancing personalized treatment approaches. Participants will undergo assessments to evaluate the medication's impact on brain activity and drinking behaviors in a controlled environment. By focusing on precision medicine, the research seeks to improve treatment outcomes for individuals struggling with AUD.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alcohol Use Disorder who are interested in exploring new treatment options.
Not a fit: Patients who do not have Alcohol Use Disorder or those who are not interested in pharmacological treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective, personalized treatment options for individuals with Alcohol Use Disorder.
How similar studies have performed: Previous research has shown promise in using genetic factors to predict responses to medications for Alcohol Use Disorder, suggesting that this approach may yield valuable insights.
Where this research is happening
Aurora, UNITED STATES
- UNIVERSITY OF COLORADO DENVER — Aurora, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SCHACHT, JOSEPH P. — UNIVERSITY OF COLORADO DENVER
- Study coordinator: SCHACHT, JOSEPH P.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.