Investigating a new kidney disease linked to agricultural chemicals
Chronic kidney disease of unknown etiology: applying a multidisciplinary approach to investigate the world's most common tubulointerstitial kidney disease
This study is looking into how certain chemicals in water might be causing kidney problems in farming communities, and it's for people who have chronic kidney disease that doctors can't explain.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11066429 on NIH RePORTER |
What this research studies
This research focuses on chronic kidney disease of unknown etiology (CKDu), which has emerged in agricultural communities worldwide. The study aims to understand the potential link between CKDu and exposure to agrochemicals through contaminated water sources. Researchers will collect environmental samples and conduct kidney biopsies on participants who meet specific clinical criteria. By analyzing these samples, the team hopes to identify the specific chemicals responsible for this serious health issue.
Who could benefit from this research
Good fit: Ideal candidates for participation are agricultural workers who have been exposed to contaminated water and are at risk for CKDu.
Not a fit: Patients who do not work in agricultural settings or who do not have exposure to the identified agrochemicals may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention of CKDu, ultimately saving lives and improving health outcomes for affected individuals.
How similar studies have performed: Previous studies have indicated a potential link between agrochemical exposure and CKDu, suggesting that this research builds on existing findings rather than being entirely novel.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Anand, Shuchi — Stanford University
- Study coordinator: Anand, Shuchi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.