Investigating a new HIV vaccine approach using nonhuman primates

Assessment of Heterologous Prime-boost HIV Vaccine Regimen to Elicit Cross-reactive Neutralizing Antibodies Targeting HIV Fusion Peptide

NIH-funded research Tulane University of Louisiana · NIH-11193362

This study is working on creating a better HIV vaccine by testing it in monkeys to see how well it can protect against the virus, and it’s all about finding ways to make the vaccine stronger and more effective for people living with HIV.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionTulane University of Louisiana NIH-funded
Lab location1 site (New Orleans, United States)
Project IDNIH-11193362 on NIH RePORTER

What this research studies

This research focuses on developing an effective HIV vaccine by utilizing nonhuman primates (NHPs) in preclinical studies. The project aims to evaluate candidate AIDS vaccines through thorough assessments of immune responses and vaccine efficacy in NHP models. By identifying correlates of reduced risk of HIV infection, the research seeks to enhance the immunogenicity and effectiveness of potential vaccines. The study will also support the breeding and maintenance of NHPs to facilitate ongoing vaccine research.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals at high risk for HIV infection who may benefit from new prevention strategies.

Not a fit: Patients who are already HIV-positive or those who do not meet the criteria for high-risk populations may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of a vaccine that effectively prevents or controls HIV infection.

How similar studies have performed: Previous research has shown promise in developing HIV vaccines using similar approaches, although this specific methodology is still being explored.

Where this research is happening

New Orleans, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.