Investigating a new HIV vaccine approach using nonhuman primates
Official title: Assessment of Heterologous Prime-boost HIV Vaccine Regimen to Elicit Cross-reactive Neutralizing Antibodies Targeting HIV Fusion Peptide
Funded at Tulane University of Louisiana · NIH-11193362 · Data updated 2026-11-12
This study is working on creating a better HIV vaccine by testing it in monkeys to see how well it can protect against the virus, and it’s all about finding ways to make the vaccine stronger and more effective for people living with HIV.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tulane University of Louisiana NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project start | September 13, 2024 |
| Project end | April 11, 2027 |
| Funding year | 2024 |
| Award (this year) | $1,722,748 |
| NIH project number | 75N93020D00007-0-759302400002-1 |
| Project ID | NIH-11193362 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at high risk for HIV infection who may benefit from new prevention strategies.
✕Less likely to help
Patients who are already HIV-positive or those who do not meet the criteria for high-risk populations may not benefit from this research.
What this research studies
This research focuses on developing an effective HIV vaccine by utilizing nonhuman primates (NHPs) in preclinical studies. The project aims to evaluate candidate AIDS vaccines through thorough assessments of immune responses and vaccine efficacy in NHP models. By identifying correlates of reduced risk of HIV infection, the research seeks to enhance the immunogenicity and effectiveness of potential vaccines. The study will also support the breeding and maintenance of NHPs to facilitate ongoing vaccine research.
Why it matters
Potential benefit: If successful, this research could lead to the development of a vaccine that effectively prevents or controls HIV infection.
How similar studies have gone: Previous research has shown promise in developing HIV vaccines using similar approaches, although this specific methodology is still being explored.
Where this research is happening
-
Tulane University of Louisiana
New Orleans, United States Active
Researchers
- Principal investigator: Veazey, Ronald — Tulane University of Louisiana
- Study coordinator: Veazey, Ronald
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.