Investigating a new gene related to age-related macular degeneration
Nuclear encoded Humanin Isoforms and Mitochondria in Age-related Macular Degeneration
['FUNDING_R21'] · STATE UNIVERSITY OF NEW YORK AT BUFFALO · NIH-11062896
This study is looking at a specific gene that might be important in understanding how age-related macular degeneration (AMD) develops, with the hope that what they learn could help create better treatments for people dealing with this eye condition.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STATE UNIVERSITY OF NEW YORK AT BUFFALO (nih funded) |
| Locations | 1 site (AMHERST, UNITED STATES) |
| Trial ID | NIH-11062896 on ClinicalTrials.gov |
What this research studies
This research focuses on age-related macular degeneration (AMD), a leading cause of blindness in older adults. The study aims to identify a novel gene, MTRNR2L1, which may play a crucial role in the disease's progression. By examining how this gene is affected by factors like oxidative stress and inflammation, researchers hope to uncover new treatment targets. Patients may benefit from insights that could lead to improved therapies for preventing or managing AMD.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing early signs of age-related macular degeneration.
Not a fit: Patients with advanced stages of age-related macular degeneration who are already receiving treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment options that prevent the onset of advanced age-related macular degeneration.
How similar studies have performed: While this approach is novel, previous research has shown promise in targeting molecular pathways related to AMD.
Where this research is happening
AMHERST, UNITED STATES
- STATE UNIVERSITY OF NEW YORK AT BUFFALO — AMHERST, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ZHANG, SARAH X — STATE UNIVERSITY OF NEW YORK AT BUFFALO
- Study coordinator: ZHANG, SARAH X
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: age related macular disease