Investigating a new exercise program for patients with peripheral artery disease
The effects of a novel, non-ischemic and pain-free exercise intervention in peripheral artery disease
['FUNDING_R01'] · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · NIH-10904669
This study is testing a new exercise program called Non-IsChemic Exercise (NICE) for people with peripheral artery disease (PAD) to see if it can help them walk better and feel healthier without causing pain, compared to a regular exercise program that might hurt.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR (nih funded) |
| Locations | 1 site (OKLAHOMA CITY, UNITED STATES) |
| Trial ID | NIH-10904669 on ClinicalTrials.gov |
What this research studies
This research focuses on a novel exercise intervention called Non-IsChemic Exercise (NICE) designed specifically for patients with peripheral artery disease (PAD). The program aims to improve walking ability, quality of life, and vascular health without causing pain or ischemia, which are common issues with traditional exercise methods. Participants will be randomly assigned to either the NICE program or a standard painful exercise program, allowing researchers to compare the outcomes in terms of ambulation and health-related quality of life. The study will also explore changes in microvascular function and systemic biomarkers associated with these exercise interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above who have been diagnosed with peripheral artery disease.
Not a fit: Patients who are younger than 65 or do not have peripheral artery disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a more effective and pain-free exercise option for patients with peripheral artery disease, enhancing their mobility and overall quality of life.
How similar studies have performed: Previous research has shown promising results with non-painful exercise interventions in similar patient populations, suggesting that this approach may be effective.
Where this research is happening
OKLAHOMA CITY, UNITED STATES
- UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR — OKLAHOMA CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GARDNER, ANDREW W — UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
- Study coordinator: GARDNER, ANDREW W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.