Investigating a new enzyme's role in liver fat regulation
Official title: Role of a Novel Methyltransferase in Liver Lipid Metabolism
Funded at University of California Los Angeles · NIH-11073112 · Data updated 2026-11-12
This study is looking at how a new enzyme affects fat processing in the liver, which could help find better treatments for liver problems that involve fat metabolism, so it’s important for anyone dealing with these conditions.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | April 10, 2024 |
| Project end | February 28, 2029 |
| Funding year | 2025 |
| Award (this year) | $170,532 |
| NIH project number | 5K08DK136706-02 |
| Project ID | NIH-11073112 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with liver disorders or metabolic conditions affecting lipid levels.
✕Less likely to help
Patients with non-liver related metabolic disorders or those without any lipid metabolism issues may not receive benefit from this research.
What this research studies
This research focuses on understanding how a novel methyltransferase enzyme affects lipid metabolism in the liver. The principal investigator, Dr. Alexander Nguyen, will explore the gene expression and regulatory mechanisms involved in liver lipid homeostasis. By utilizing advanced techniques and mentorship from leading experts, the research aims to uncover new insights that could lead to improved treatments for liver-related conditions. Patients may benefit from the findings as they could inform future therapies targeting lipid metabolism disorders.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for managing liver diseases related to lipid metabolism.
How similar studies have gone: Other research has shown success in exploring lipid metabolism, indicating that this approach has the potential for meaningful advancements.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Nguyen, Alexander — University of California Los Angeles
- Study coordinator: Nguyen, Alexander
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.