Investigating a new diet to promote healthy aging and metabolic health.
Official title: Translational analysis of a novel intervention to promote healthy aging.
Funded at University of Wisconsin-Madison · NIH-10905341 · Data updated 2026-11-12
This study is looking at how changing what older adults eat can help them stay healthier and lower their chances of getting diseases like type 2 diabetes and Alzheimer's, by testing diets that might improve their metabolism.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $659,916 |
| NIH project number | 1R01AG085898-01A1 |
| Project ID | NIH-10905341 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 65 and older who are experiencing obesity or metabolic issues.
✕Less likely to help
Patients under 65 years of age or those without metabolic health concerns may not benefit from this research.
What this research studies
This research focuses on how specific dietary changes can help older adults maintain better metabolic health and reduce the risk of age-related diseases like type 2 diabetes and Alzheimer's. The study will test diets that lower certain amino acids, which have shown promise in reducing obesity and improving insulin sensitivity in previous animal studies. By analyzing the effects of these diets on both mice and non-human primates, researchers aim to understand the best dietary strategies for promoting healthy aging. Participants may benefit from insights into dietary interventions that could enhance their overall health as they age.
Why it matters
Potential benefit: If successful, this research could lead to dietary recommendations that significantly improve metabolic health and reduce the risk of chronic diseases in older adults.
How similar studies have gone: Previous research has shown that dietary modifications can effectively improve metabolic health, suggesting a promising avenue for this novel approach.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Colman, Ricki J — University of Wisconsin-Madison
- Study coordinator: Colman, Ricki J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.