Investigating a new approach to restore vision in blind individuals using flexible electrodes.

Longitudinal neuronal and behavioral responses to microstimulation of LGN by ultraflexible electrodes

NIH-funded research Rice University · NIH-11049749

This study is working on a new device to help people who are blind see again by using special flexible electrodes to connect with a part of the brain, aiming to give them a better view of the world and more independence.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRice University NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-11049749 on NIH RePORTER

What this research studies

This research focuses on developing a novel visual prosthesis aimed at restoring sight for individuals who are blind. By utilizing ultraflexible electrodes to interface with the lateral geniculus nucleus (LGN) in the brain, the project seeks to overcome the limitations of current visual prosthetic devices. The approach involves bioengineering techniques to create a device that can provide a broader visual field and better tissue compatibility for long-term use. Patients may benefit from improved visual perception and autonomy through this innovative technology.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who are blind due to conditions that prevent the use of traditional retinal prostheses.

Not a fit: Patients with intact retinal function or those whose blindness is not related to the visual pathways targeted by this research may not benefit.

Why it matters

Potential benefit: If successful, this research could significantly enhance the quality of life for blind individuals by restoring their visual function.

How similar studies have performed: While there have been advancements in retinal and cortical prostheses, this specific approach using ultraflexible electrodes in the LGN is relatively novel and has not been extensively tested.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.