Investigating a malaria vaccine candidate to improve protection in children
Analyzing the function and antibody-mediated inhibition of the malaria vaccine candidate PF3D7_1136200
This study is looking at a protein from the malaria parasite to see how it can help create a better vaccine for young children under 5, by figuring out how antibodies against this protein can protect them from malaria.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Science Center NIH-funded |
| Lab location | 1 site (San Antonio, United States) |
| Project ID | NIH-10824946 on NIH RePORTER |
What this research studies
This research focuses on understanding how a specific protein from the malaria parasite, PF3D7_1136200, can help develop a more effective vaccine for malaria, particularly for children under 5 years old. The study aims to analyze how antibodies against this protein can inhibit the malaria parasite and contribute to immunity. By exploring the relationship between antibody responses and protection from malaria, the research seeks to identify ways to enhance vaccine efficacy, especially in regions where malaria is prevalent.
Who could benefit from this research
Good fit: Ideal candidates for this research are children under the age of 5 living in malaria-endemic regions.
Not a fit: Patients who are not children or those living in non-endemic malaria regions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a more effective malaria vaccine that significantly reduces the incidence of severe malaria in young children.
How similar studies have performed: Previous research has shown promising results with similar approaches targeting malaria vaccine development, indicating potential for success in this area.
Where this research is happening
San Antonio, United States
- University of Texas Hlth Science Center — San Antonio, United States (Active)
Researchers
- Principal investigator: Garza, Rolando — University of Texas Hlth Science Center
- Study coordinator: Garza, Rolando
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.