Investigating a ketogenic diet for managing type 1 diabetes
EFFICACY AND SAFETY OF A KETOGENIC DIET IN TYPE 1 DIABETES
['FUNDING_R01'] · WASHINGTON UNIVERSITY · NIH-11061384
This study is looking at how a very-low-carb ketogenic diet might help people with type 1 diabetes by making their blood sugar levels more stable and reducing the amount of insulin they need, all while keeping an eye on their safety.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-11061384 on ClinicalTrials.gov |
What this research studies
This research explores the effects of a very-low-carbohydrate ketogenic diet on individuals with type 1 diabetes. The study aims to determine if this diet can help reduce blood sugar variability and lower insulin requirements, potentially improving overall diabetes management. Participants will be monitored for safety and tolerability, as there are concerns about risks such as hypoglycemia and diabetic ketoacidosis. The research will be conducted at two sites, allowing for a comprehensive evaluation of the diet's efficacy.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with type 1 diabetes who are seeking alternative methods to manage their condition.
Not a fit: Patients who do not have type 1 diabetes or those who are unable to adhere to a strict dietary regimen may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new dietary approach to better manage type 1 diabetes and reduce reliance on insulin.
How similar studies have performed: While there have been observational studies suggesting benefits of a ketogenic diet in type 1 diabetes, this research is novel as it aims to conduct randomized controlled trials for longer durations.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KLEIN, SAMUEL — WASHINGTON UNIVERSITY
- Study coordinator: KLEIN, SAMUEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.