Investigating a brain network that may help predict recovery of consciousness after brain injury
A functional brain network to detect and predict consciousness recovery
This study is looking at how a special brain network works in people who have had serious brain injuries, using advanced imaging to see how it connects to their awareness and chances of recovery, all to help improve diagnosis and treatment for those with consciousness disorders.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11054803 on NIH RePORTER |
What this research studies
This research focuses on understanding how a specific brain network, known as the arousal-awareness integration network (AAIN), functions in patients who have suffered acute brain injuries. Using advanced imaging techniques like functional magnetic resonance imaging (fMRI), the study aims to explore how changes in this network's connectivity relate to levels of consciousness and the potential for recovery. By examining patients in the intensive care unit, the research seeks to identify patterns that could inform diagnostic and therapeutic strategies for disorders of consciousness.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced acute brain injuries and are currently in the intensive care unit.
Not a fit: Patients with chronic brain injuries or those who are not currently experiencing disorders of consciousness may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for diagnosing and predicting recovery in patients with disorders of consciousness, ultimately enhancing patient care.
How similar studies have performed: Previous research has shown promise in using functional neuroimaging to assess consciousness recovery, suggesting that this approach could yield valuable insights.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Fischer, David Jacobson — University of Pennsylvania
- Study coordinator: Fischer, David Jacobson
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.