Investigating a botanical supplement for stress-related mental health issues
Clinical Pharmacology and Target Validation of BDPP for Stress-Related Disorders
This study is looking at a plant-based supplement that might help reduce the negative effects of stress on mental health, especially for people dealing with anxiety and depression, by seeing how it affects the body's immune response.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10886090 on NIH RePORTER |
What this research studies
This research explores the potential of a botanical supplement enriched with polyphenols to mitigate the harmful effects of stress, which is a significant risk factor for mental health disorders like major depressive disorder. The study focuses on how this supplement may influence immune responses, particularly the production of inflammatory markers such as interleukin-6, which have been linked to stress-induced anxiety and depression. By examining the supplement's effects on both central and peripheral immune activity, the research aims to provide a new treatment avenue for patients who do not respond to current therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing stress-related mental health issues, particularly those with treatment-resistant depression or anxiety.
Not a fit: Patients who do not have stress-related mental health disorders or those who are already responding well to existing treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could offer a novel treatment option for patients suffering from stress-related mental health disorders, particularly those who are resistant to existing therapies.
How similar studies have performed: Previous research has shown promising results with botanical supplements in managing stress-related conditions, suggesting that this approach may be viable.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Murrough, James Warren — Icahn School of Medicine at Mount Sinai
- Study coordinator: Murrough, James Warren
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.