International URBAN ARCH Center on alcohol, HIV, and tuberculosis
The International URBAN Alcohol Research Collaboration on HIV/AIDS (ARCH) Center
Finding how alcohol use affects tuberculosis risk and long-term lung health in people living with HIV.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11146586 on NIH RePORTER |
What this research studies
If you join, researchers will follow people living with HIV who drink alcohol across sites in Uganda, Russia, and Boston to track new TB infections, TB disease after preventive therapy, and lung health after TB treatment. Participants may have clinical visits, breathing tests, imaging, and give samples like blood or sputum for lab work. The program combines data from multiple countries to see whether drinking raises the chance of getting TB again and contributes to lasting lung damage. Findings will guide ways to prevent TB and improve recovery for people with HIV who drink.
Who could benefit from this research
Good fit: Ideal candidates are adults living with HIV who consume alcohol and receive care at participating sites in Uganda, Russia, or Boston, including those with prior TB or on TB preventive therapy.
Not a fit: People without HIV, those who do not drink alcohol, children, or anyone not near participating sites are unlikely to be eligible or benefit directly from this project.
Why it matters
Potential benefit: Results could help develop better TB prevention and lung-care strategies tailored for people living with HIV who use alcohol.
How similar studies have performed: Previous research links heavy drinking to higher TB risk, but this international focus on TB after preventive therapy and on post-TB lung disease in people with HIV is relatively new.
Where this research is happening
Boston, United States
- Boston Medical Center — Boston, United States (Active)
Researchers
- Principal investigator: Samet, Jeffrey H. — Boston Medical Center
- Study coordinator: Samet, Jeffrey H.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.