NIH-funded research NIH-funded research

International Children and Families HIV Clinical Trials Network for Maternal and Adolescent Care

Official title: International Maternal, Adolescent and Pediatric Therapeutics Clinical Trials Network

Funded at University of California Los Angeles · NIH-11583801 · Data updated 2026-11-12

A network conducts high-quality HIV and TB clinical trials to improve treatments for pregnant women, infants, children, and adolescents affected by HIV in resource-limited settings.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles
NIH-funded
Lab location1 site (Los Angeles, United States)
Project startJanuary 1, 2014
Project endNovember 30, 2027
Funding year2026
Award (this year)$536,039
NIH project number3UM1AI106716-14S1
Project IDNIH-11583801 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates include pregnant women, infants, children, and adolescents living with HIV or at risk of infection in resource-limited settings.

Less likely to help

Results may not directly benefit individuals outside the study’s target populations or geographic settings.

What this research studies

This grant supports a network that runs clinical trials to find better HIV therapies and strategies for ART-free remission in young people and their mothers. It emphasizes improving care in pregnant women, infants, children, and adolescents, and building laboratory and research capacity in settings with high HIV burdens. The work includes developing durable treatments, assessing safety in vulnerable populations, and informing international guidelines. It also aims to address co-infections and co-morbidities that complicate HIV care in these groups.

Why it matters

Potential benefit: If successful, the research could lead to safer, more effective HIV treatments for mothers and children and improve global guidelines for care.

How similar studies have gone: Past IMPAACT trials have influenced drug labeling and guidelines for HIV care in young populations.

Where this research is happening

  • University of California Los Angeles
    Los Angeles, United States
    Active

Researchers

  • Principal investigator: Aldrovandi, Grace M — University of California Los Angeles
  • Study coordinator: Aldrovandi, Grace M

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.