Interactions between immune cells and kidney cells in a genetic kidney disease
Official title: Immune Cell and Epithelial Cell Interactions in Autosomal Dominant Polycystic Kidney Disease
Funded at Yale University · NIH-10898636 · Data updated 2026-11-12
This study is looking at how immune cells work with kidney cells in people with autosomal dominant polycystic kidney disease (ADPKD) to better understand what helps or hinders the growth of kidney cysts, which could lead to new treatment options for you.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $48,974 |
| NIH project number | 5F31DK135356-02 |
| Project ID | NIH-10898636 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with autosomal dominant polycystic kidney disease.
✕Less likely to help
Patients with other forms of kidney disease or those without a diagnosis of ADPKD may not benefit from this research.
What this research studies
This research investigates how immune cells interact with kidney epithelial cells in patients with autosomal dominant polycystic kidney disease (ADPKD). By using a specialized model, the study aims to understand the immune cell populations involved in the formation and progression of kidney cysts. Researchers will compare immune responses in different disease models to identify factors that may either promote or inhibit cyst growth. This could lead to new insights into potential treatments for ADPKD.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that slow down or prevent the progression of kidney disease in ADPKD patients.
How similar studies have gone: Previous research has indicated that immune cells play a significant role in kidney disease, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Rai, Victoria — Yale University
- Study coordinator: Rai, Victoria
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.