Intensive rehabilitation for infants with perinatal arterial stroke
Perinatal Arterial Stroke: A Multi-site RCT of Intensive Infant Rehabilitation (I-ACQUIRE)
This study is testing a new therapy program for babies aged 8 to 24 months who have had a stroke, to see if different levels of therapy can help them improve their movement and thinking skills better than the usual treatment.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Polytechnic Inst and St Univ NIH-funded |
| Lab location | 1 site (Blacksburg, United States) |
| Project ID | NIH-10589059 on NIH RePORTER |
What this research studies
This research investigates a new rehabilitation approach for infants who have experienced perinatal arterial stroke, a condition that can lead to significant disabilities. The I-ACQUIRE trial will compare two different intensities of a rehabilitation program, known as Infant ACQUIRE, against standard treatment. Infants aged 8 to 24 months will receive either moderate or high doses of therapy, focusing on operant conditioning techniques to improve their motor skills and cognitive outcomes. The treatment will take place in a familiar environment, ensuring comfort and engagement for the infants involved.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants aged 8 to 24 months who have been diagnosed with perinatal arterial stroke.
Not a fit: Patients who are older than 24 months or who do not have a diagnosis of perinatal arterial stroke may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a standardized, evidence-based rehabilitation method that significantly improves motor and cognitive outcomes for infants affected by perinatal arterial stroke.
How similar studies have performed: Previous studies of the I-ACQUIRE approach have shown promising safety and effectiveness, indicating that this method has potential for success.
Where this research is happening
Blacksburg, United States
- Virginia Polytechnic Inst and St Univ — Blacksburg, United States (Active)
Researchers
- Principal investigator: Ramey, Sharon Landesman — Virginia Polytechnic Inst and St Univ
- Study coordinator: Ramey, Sharon Landesman
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.