Integrating therapies to treat COVID-19 and its effects on the heart and lungs
ACTIV Integration of Host-targeting Therapies for COVID-19 Administrative Coordinating Center
This study is looking at new ways to help people with COVID-19 by testing different treatments that focus on how the virus affects the heart, lungs, and blood, so that patients can have better options based on solid research.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Triangle Institute NIH-funded |
| Lab location | 1 site (Research Triangle Park, United States) |
| Project ID | NIH-10171728 on NIH RePORTER |
What this research studies
This research focuses on developing and coordinating therapies that target the host response to COVID-19, particularly its impact on heart, lung, and blood health. The project will utilize adaptive platform trials, allowing for rapid testing and implementation of various treatment strategies across multiple clinical sites. By collaborating with existing clinical study networks, the research aims to streamline the process of data collection, analysis, and communication among stakeholders to ensure effective therapy development. Patients may benefit from improved treatment options that are informed by robust scientific evidence.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with COVID-19 who are experiencing cardiovascular or respiratory complications.
Not a fit: Patients who have not contracted COVID-19 or those without related cardiovascular or respiratory issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective therapies for COVID-19 that specifically address complications related to heart and lung health.
How similar studies have performed: Previous research has shown promise in using adaptive trial designs for other diseases, suggesting that this approach could be effective for COVID-19 as well.
Where this research is happening
Research Triangle Park, United States
- Research Triangle Institute — Research Triangle Park, United States (Active)
Researchers
- Principal investigator: Nolen, Tracy L — Research Triangle Institute
- Study coordinator: Nolen, Tracy L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.