Integrating therapies to treat COVID-19 and its effects on heart and lung health

ACTIV Integration of Host-targeting Therapies for COVID-19 Administrative Coordinating Center

NIH-funded research Research Triangle Institute · NIH-11005124

This study is looking for better ways to treat COVID-19 by testing different therapies that help protect your heart, lungs, and blood, and it's designed for patients who want to find effective treatments quickly.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionResearch Triangle Institute NIH-funded
Lab location1 site (Research Triangle Park, United States)
Project IDNIH-11005124 on NIH RePORTER

What this research studies

This research focuses on developing and coordinating therapies that target the host response to COVID-19, particularly its impact on heart, lung, and blood health. The project aims to conduct adaptive platform trials, which allow for the rapid testing of multiple interventions in a coordinated manner across various clinical sites. By utilizing existing clinical study networks, the research seeks to streamline the process of data collection, validation, and analysis to ensure timely and effective treatment options for patients. The Administrative Coordinating Center will facilitate collaboration among stakeholders and track progress to enhance the scientific knowledge base and inform clinical practice.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with COVID-19, particularly those experiencing complications related to heart and lung health.

Not a fit: Patients who are not infected with COVID-19 or do not have related health complications may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment options for patients suffering from COVID-19 and its associated complications.

How similar studies have performed: Previous research has shown success in adaptive platform trials for other diseases, indicating a promising approach for COVID-19 interventions.

Where this research is happening

Research Triangle Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.