Integrating HIV prevention with TB household contact evaluation
Official title: TB PrEP - Integrating HIV prevention with TB household contact evaluation
Funded at University of Washington · NIH-11008075 · Data updated 2026-11-12
This study is looking at how to help people living in homes with tuberculosis (TB) get HIV prevention medicine called PrEP more easily, especially in places like Uganda where both TB and HIV are common.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | September 9, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $707,687 |
| NIH project number | 1R01MH134685-01A1 |
| Project ID | NIH-11008075 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals aged 21 and older who are HIV-negative and live in households with a confirmed TB case.
✕Less likely to help
Patients who are already HIV-positive or do not have any exposure to TB may not benefit from this research.
What this research studies
This research investigates how to effectively provide HIV pre-exposure prophylaxis (PrEP) to individuals living in households affected by tuberculosis (TB). It focuses on integrating HIV testing and PrEP access into TB contact investigations, particularly in high-prevalence areas like Uganda. By evaluating the effectiveness of this approach, the research aims to ensure that those at high risk of HIV due to their TB exposure receive the preventive care they need. The study will adapt existing successful models to improve access to PrEP for vulnerable populations.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of HIV among individuals living in TB-affected households.
How similar studies have gone: Previous studies have shown that integrating PrEP into household-based TB contact investigations is feasible and effective in similar high HIV-burden settings.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Ross, Jennifer M — University of Washington
- Study coordinator: Ross, Jennifer M
Related research
Other NIH-funded projects on the same topics.
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Harnessing male peer networks to boost HIV testing and PrEP use
A large clinical trial in South Africa tests whether giving HIV self-test kits through male peer networks, with phone support, increases PrEP uptake among men.
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Harnessing men's peer networks to boost HIV self-testing and PrEP use
A large project in South Africa tests whether giving HIV self-test kits through men’s social networks, with phone support, can lead to more men starting PrEP and using HIV testing.
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TB PrEP: Bringing HIV prevention to households affected by TB in Uganda
Aims to help people in households with TB in Uganda access HIV PrEP as part of a combined prevention approach.
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How choosing PrEP products could improve HIV protection for young women in Kenya
This project looks at which HIV-prevention options young Kenyan women prefer and how choosing a product affects how well they stay protected.
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Effectiveness of PrEP product choice for HIV prevention among young Kenyan women seeking reproductive health services
A study tests which PrEP options best help young Kenyan women stay protected against HIV when they access reproductive health services.
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Nurse-led group program to boost PrEP use for women at risk of HIV
A nurse-developed, three-session group program helps women in midwestern cities start and stay on PrEP to prevent HIV.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.