Integrating gene function and biological pathways for better biomedical research tools
Reactome and the Gene Ontology: Digital pathway convergence for core data resources
This study is working on making it easier for scientists to understand how genes work together in our bodies by combining two important databases, so they can find helpful information more easily when studying health and disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10865045 on NIH RePORTER |
What this research studies
This research aims to enhance the integration of the Gene Ontology (GO) and Reactome databases, which provide critical information about gene functions and biological pathways. By developing tools to connect these resources, the project will create a more comprehensive and user-friendly platform for researchers in the biomedical field. This integration will allow for better understanding of how genes interact within biological processes, ultimately aiding in the analysis of complex biological systems. The work will leverage the GO Causal Activity Model to facilitate this integration, making it easier for researchers to access and utilize this valuable information.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include researchers and scientists working in the fields of genetics, molecular biology, and bioinformatics.
Not a fit: Patients with no involvement in biomedical research or those not engaged in genetic studies may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the tools available for biomedical research, leading to better insights into gene functions and disease mechanisms.
How similar studies have performed: Previous research has shown success in integrating biological databases, indicating that this approach has the potential for meaningful advancements in the field.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Deustachio, Peter G — New York University School of Medicine
- Study coordinator: Deustachio, Peter G
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.