Innovative technology for analyzing individual cells in cancer
Official title: Advanced Single Cell Technology Innovation Core
Funded at Columbia University Health Sciences · NIH-11171868 · Data updated 2026-11-12
This study is exploring new ways to look closely at individual cells in tumors to better understand how they work together and contribute to cancer, which could help create more effective treatments for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 19, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $259,748 |
| NIH project number | 5U54CA274506-02 |
| Project ID | NIH-11171868 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with various types of cancer who are interested in contributing to advancements in cancer treatment.
✕Less likely to help
Patients with non-cancerous conditions or those not diagnosed with cancer may not receive any benefit from this research.
What this research studies
This research focuses on developing advanced technologies to analyze individual cells within tumors, aiming to understand the different cell states that contribute to cancer progression. By utilizing cutting-edge methods like single-cell RNA sequencing and CRISPR techniques, the project seeks to provide insights into how cells interact and function within the tumor microenvironment. Patients may benefit from the enhanced understanding of cancer biology, which could lead to more targeted and effective treatments.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in personalized cancer therapies by identifying specific cell behaviors and interactions that drive tumor growth.
How similar studies have gone: Other research has shown success with similar single-cell analysis approaches, indicating a promising avenue for understanding complex diseases like cancer.
Where this research is happening
-
Columbia University Health Sciences
New York, United States Active
Researchers
- Principal investigator: Sims, Peter Alan — Columbia University Health Sciences
- Study coordinator: Sims, Peter Alan
Related research
Other NIH-funded projects on the same topics.
-
Precision phenotyping of emphysema in the elderly: a study in diverse adults
Researchers will look at CT scans and lung tests in older adults to understand different forms of emphysema and how they relate to health outcomes.
-
HPV-based cervical cancer screening and treatment implementation in resource-limited settings
A collaborative project to help doctors in South Africa put HPV-based screening and same-day treatment for cervical cancer into routine care, so more people get fast, effective care.
-
Cervical cancer screening and treatment rollout in resource-poor settings
A team from Columbia and the University of Cape Town is testing how to best implement affordable, same-day HPV-based screen-and-treat for cervical cancer in public health settings.
-
Understanding SCN3A-related Developmental Epileptic Encephalopathy and Finding Better Treatments
This NIH grant focuses on how SCN3A gene variants cause developmental epileptic encephalopathy and aims to develop more effective therapies for affected patients.
-
mChoice: Boosting PrEP Use and Adherence for Black and Latino MSM with Tailored Training and Support
A national study to help Black and Latino men who have sex with men start and stick with PrEP through culturally matched provider training and patient support.
-
M-CaRE: Mobile clinics and a smart heart-lung care tool for multimorbidity
A mobile, multilingual tool plus community health workers will help screen and manage high blood pressure and COPD in diverse adult patients, especially in underserved areas.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.