NIH-funded research NIH-funded research

Innovative polymer fibers for non-drug contraceptive devices

Official title: SMART Polymer Fibers For Tampon-Like Nonsteroidal Contraceptive Devices

Funded at St. Louis College of Pharmacy · NIH-10831242 · Data updated 2026-11-12

This study is exploring a new type of smart fiber that can help prevent pregnancy by creating a temporary barrier to sperm in the female reproductive system, offering a quick and easy non-hormonal birth control option for those looking for alternatives.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionSt. Louis College of Pharmacy
NIH-funded
Lab location1 site (St. Louis, UNITED STATES)
Project startSeptember 13, 2019
Project endAugust 31, 2025
Funding year2023
Award (this year)$109,174
NIH project number3R33HD099748-05S1
Project IDNIH-10831242 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are women seeking non-hormonal contraceptive options.

Less likely to help

Patients who are not seeking contraception or those who have contraindications to using vaginal devices may not benefit from this research.

What this research studies

This research investigates the development of smart polymer fibers designed to create a temporary barrier to sperm in the female reproductive tract. By utilizing bioresponsive materials that react to seminal fluid, these fibers aim to maintain an acidic environment that hinders sperm motility, thereby providing a non-steroidal contraceptive option. The approach is innovative as it seeks to offer a rapid and cost-effective alternative to traditional contraceptive methods, with the potential to reach human testing more quickly. Patients may benefit from a new form of contraception that is easy to use and does not involve hormonal drugs.

Why it matters

Potential benefit: If successful, this research could provide women with a novel, non-hormonal contraceptive method that is effective and easy to use.

How similar studies have gone: While this approach is innovative, similar bioengineering concepts in contraceptive development have shown promise, indicating potential for success.

Where this research is happening

  • St. Louis College of Pharmacy
    St. Louis, United States
    Active

Researchers

  • Principal investigator: Pauletti, Giovanni M — St. Louis College of Pharmacy
  • Study coordinator: Pauletti, Giovanni M

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.