NIH-funded research R01 grant

Innovative methods to understand cancer risk and outcomes

Official title: Methodologic Innovations in Cancer Epidemiology

Funded at Brigham and Women's Hospital · NIH-11031990 · Data updated 2026-11-12

This study is looking at how different factors can affect the development and progression of colorectal cancer, with the goal of helping patients by creating better ways to predict outcomes and improve prevention and treatment strategies.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBrigham and Women's Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startMarch 1, 2023
Project endFebruary 28, 2027
Funding year2025
Award (this year)$447,434
NIH project number5R01CA272489-03
Project IDNIH-11031990 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals at risk for colorectal cancer, particularly those with a history of advanced polyps or other related risk factors.

Less likely to help

Patients with cancers unrelated to colorectal cancer or those who are not at risk for developing colorectal cancer may not benefit from this research.

What this research studies

This research investigates how different risk factors contribute to the development and progression of cancers, particularly colorectal cancer. It aims to create advanced models that analyze exposure data before and after cancer diagnosis to better predict outcomes. By examining various stages of cancer development, including the formation of polyps and subsequent cancer incidence, the study seeks to improve understanding of how these factors influence survival rates. Patients may benefit from insights that could lead to more personalized prevention and treatment strategies.

Why it matters

Potential benefit: If successful, this research could lead to improved cancer risk assessment and tailored prevention strategies for patients.

How similar studies have gone: Previous research has shown promise in using innovative modeling approaches to understand cancer risk factors, suggesting that this methodology could yield valuable insights.

Where this research is happening

  • Brigham and Women's Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Rosner, Bernard a — Brigham and Women's Hospital
  • Study coordinator: Rosner, Bernard a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.