Innovative heart assist devices for children with heart failure

Multifunctional VAD Technology for High-Risk Pediatric Patients

['FUNDING_R01'] · DREXEL UNIVERSITY · NIH-10883981

This study is working on a new heart support device for kids with serious heart problems, aiming to make it safer and more effective so they can feel better and live healthier lives.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorDREXEL UNIVERSITY (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-10883981 on ClinicalTrials.gov

What this research studies

This research focuses on developing advanced ventricular assist devices (VADs) specifically designed for high-risk pediatric patients suffering from heart failure due to congenital or acquired heart disease. The project aims to create a next-generation device that minimizes blood damage and improves blood flow, addressing the unique physiological needs of children. By utilizing innovative design and technology, the research seeks to enhance the safety and effectiveness of heart support for young patients, ultimately improving their quality of life. The approach includes in vitro testing and iterative design to ensure the device meets the specific requirements of pediatric patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are pediatric patients with heart failure who require mechanical support due to congenital or acquired heart conditions.

Not a fit: Patients who do not have heart failure or those who are not eligible for mechanical heart support may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide safer and more effective heart assist devices for children, significantly improving their treatment outcomes.

How similar studies have performed: Previous research has shown promise in developing advanced heart assist technologies for adults, but this specific focus on pediatric patients represents a novel and critical area of innovation.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.