Injectable platform for regenerating alveolar bone
Biomimetic and Injectable Highly Porous Nanofiber Microsphere-based Platform for Alveolar Bone Regeneration
['FUNDING_R01'] · UNIVERSITY OF NEBRASKA MEDICAL CENTER · NIH-10798229
This study is testing a new injectable treatment that helps heal and rebuild the bone in your jaw, making it easier to keep your teeth and dental implants, especially if you've lost bone from gum disease or injury.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF NEBRASKA MEDICAL CENTER (nih funded) |
| Locations | 1 site (OMAHA, UNITED STATES) |
| Trial ID | NIH-10798229 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a new injectable therapy to regenerate alveolar bone, which is essential for retaining teeth and dental implants. The approach utilizes highly porous nanofiber microspheres that allow cells to attach and grow, promoting bone healing without the need for extensive surgical procedures. This method aims to address the challenges faced by patients who have lost bone due to periodontal disease or trauma, providing a less invasive alternative to traditional bone grafts. The research involves testing this innovative therapy in preclinical models to evaluate its effectiveness in healing bone defects.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who have experienced alveolar bone loss due to periodontal disease or trauma and require dental implants.
Not a fit: Patients with intact alveolar bone or those who do not require dental implants may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a safer and more effective method for patients to regenerate alveolar bone, improving outcomes for dental implant procedures.
How similar studies have performed: Other research has shown promise in using biomimetic materials for bone regeneration, indicating potential success for this novel approach.
Where this research is happening
OMAHA, UNITED STATES
- UNIVERSITY OF NEBRASKA MEDICAL CENTER — OMAHA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: XIE, JINGWEI — UNIVERSITY OF NEBRASKA MEDICAL CENTER
- Study coordinator: XIE, JINGWEI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: bone disorder, Bone Diseases