Injectable hydrogel to help regenerate damaged neural tissues
Bioelectronics-embedded injectable hydrogel for neural regeneration
This study is testing a new gel that can help deliver special cells to heal damaged nerves, like those hurt in spinal cord injuries, and it aims to improve recovery and restore movement for patients.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of New Hampshire NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10647492 on NIH RePORTER |
What this research studies
This research focuses on developing a new type of injectable hydrogel designed to deliver neural stem cells (NSCs) for the regeneration of damaged neural tissues, such as those affected by spinal cord injuries. The hydrogel is made from composite microgels that allow for better cell viability and promote essential cell-to-cell interactions necessary for the differentiation of NSCs into neurons. By using a dual crosslinking mechanism, the hydrogel creates a microporous structure that supports the growth and integration of these cells into the host tissue, potentially leading to improved recovery of neural function. Patients receiving this treatment could benefit from enhanced healing and restoration of neural pathways.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from spinal cord injuries or other neural damage who are seeking innovative treatment options.
Not a fit: Patients with non-neural injuries or those who do not have the capacity for neural regeneration may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve recovery outcomes for patients with neural injuries by enhancing the regeneration of damaged tissues.
How similar studies have performed: While the approach of using injectable hydrogels for cell delivery is being explored, this specific microporous formulation represents a novel advancement in the field.
Where this research is happening
Durham, United States
- University of New Hampshire — Durham, United States (Active)
Researchers
- Principal investigator: Jeong, Kyung Jae — University of New Hampshire
- Study coordinator: Jeong, Kyung Jae
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.