NIH-funded research R01 grant

Infertility and long-term health in Hispanic women of Mexican heritage

Official title: Infertility and Long-Term Health Outcomes Among Hispanic Women with Mexican Heritage

Funded at University of Arizona · NIH-11175413 · Data updated 2026-11-12

This project looks at whether having trouble getting pregnant is linked to later risks of cancer, diabetes, and heart-related disease in Hispanic women with Mexican roots.

More Infertility research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Arizona
NIH-funded
Lab location1 site (Tucson, United States)
Project startAugust 22, 2024
Project endJune 30, 2029
Funding year2025
Award (this year)$465,871
NIH project number5R01HD114871-02
Project IDNIH-11175413 on NIH RePORTER

Who could benefit from this research

Could help

Women of Hispanic ethnicity, especially those of Mexican heritage, who have experienced infertility (trying to conceive for ≥12 months) or who have diagnoses like PCOS, endometriosis, or tubal factor infertility would be the focus.

Less likely to help

Women without a history of infertility or women from non-Hispanic or non-Mexican backgrounds may not receive direct, specific benefits from findings tailored to Mexican-heritage women.

What this research studies

Researchers will use data already collected from the Mexican Teachers' Cohort, a group of over 115,000 women followed for about 18 years, to study reproductive histories and specific infertility diagnoses like PCOS, endometriosis, tubal factor, and male factor. They will connect those reproductive records to validated health outcomes such as breast and ovarian cancer, adult-onset diabetes, and cardiometabolic events. The team will compare women who reported infertility or received infertility treatments to those who did not, and look for differences in long-term disease risk by infertility cause and treatment. Findings will focus on women with Mexican heritage to address gaps in prior research.

Why it matters

Potential benefit: If successful, this work could help identify groups of women with infertility who may benefit from earlier screening or targeted prevention for cancer and cardiometabolic disease.

How similar studies have gone: Earlier studies have linked infertility to higher risks of cancer and cardiometabolic disease, but few large, long-term cohorts have specifically studied Hispanic women of Mexican heritage, so this work builds on prior signals with a much larger, focused dataset.

Where this research is happening

  • University of Arizona
    Tucson, United States
    Active

Researchers

  • Principal investigator: Farland, Leslie V — University of Arizona
  • Study coordinator: Farland, Leslie V

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.