Infertility and long-term health in Hispanic women of Mexican heritage

Infertility and Long-Term Health Outcomes Among Hispanic Women with Mexican Heritage

NIH-funded research University of Arizona · NIH-11175413

This project looks at whether having trouble getting pregnant is linked to later risks of cancer, diabetes, and heart-related disease in Hispanic women with Mexican roots.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Arizona NIH-funded
Lab location1 site (Tucson, United States)
Project IDNIH-11175413 on NIH RePORTER

What this research studies

Researchers will use data already collected from the Mexican Teachers' Cohort, a group of over 115,000 women followed for about 18 years, to study reproductive histories and specific infertility diagnoses like PCOS, endometriosis, tubal factor, and male factor. They will connect those reproductive records to validated health outcomes such as breast and ovarian cancer, adult-onset diabetes, and cardiometabolic events. The team will compare women who reported infertility or received infertility treatments to those who did not, and look for differences in long-term disease risk by infertility cause and treatment. Findings will focus on women with Mexican heritage to address gaps in prior research.

Who could benefit from this research

Good fit: Women of Hispanic ethnicity, especially those of Mexican heritage, who have experienced infertility (trying to conceive for ≥12 months) or who have diagnoses like PCOS, endometriosis, or tubal factor infertility would be the focus.

Not a fit: Women without a history of infertility or women from non-Hispanic or non-Mexican backgrounds may not receive direct, specific benefits from findings tailored to Mexican-heritage women.

Why it matters

Potential benefit: If successful, this work could help identify groups of women with infertility who may benefit from earlier screening or targeted prevention for cancer and cardiometabolic disease.

How similar studies have performed: Earlier studies have linked infertility to higher risks of cancer and cardiometabolic disease, but few large, long-term cohorts have specifically studied Hispanic women of Mexican heritage, so this work builds on prior signals with a much larger, focused dataset.

Where this research is happening

Tucson, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes MellitusBreast CancerBreast Cancer Risk FactorCancersCardiometabolic Disease
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.