Infant Genomic Sequencing to Guide Lifelong Care
Official title: Long-term Impact and Value of Infant Genomic Sequencing (LIVING)
Funded at Harvard Pilgrim Health Care, INC. · NIH-11336311 · Data updated 2026-11-12
This project looks at how sequencing babies at birth could inform healthier, long-term care for children and help tailor medications as they grow.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Pilgrim Health Care, INC. NIH-funded |
| Lab location | 1 site (Canton, UNITED STATES) |
| Project start | September 1, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $704,548 |
| NIH project number | 5R01HD114807-03 |
| Project ID | NIH-11336311 on NIH RePORTER |
Who could benefit from this research
✓Could help
Newborns and young children whose families and healthcare providers are considering genomic information as part of care.
✕Less likely to help
Some families may experience limited benefit if sequencing results do not change clinical management or if findings are uncertain.
What this research studies
The study explores sequencing newborns to identify existing conditions and predispositions to disease, with a focus on how results could influence ongoing medical decisions. It also examines how genetic information related to drug metabolism could guide medication choices over time. Researchers will study how to implement newborn genomic sequencing within health systems and how families and providers experience the process. The goal is to understand long-term effects, benefits, and challenges of using sequencing results in routine pediatric care.
Why it matters
Potential benefit: If successful, families may receive more personalized medical care for their child from birth onward, potentially preventing or mitigating health issues.
How similar studies have gone: Past work has shown feasibility of newborn sequencing; this grant aims to address long-term impact and care integration.
Where this research is happening
-
Harvard Pilgrim Health Care, INC.
Canton, United States Active
Researchers
- Principal investigator: Christensen, Kurt Derek — Harvard Pilgrim Health Care, INC.
- Study coordinator: Christensen, Kurt Derek
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.