Increasing access to naloxone to prevent opioid overdoses in syringe service programs

Improving Equitable Access to Naloxone to Prevent Opioid Overdose Deaths Within Syringe Service Programs

NIH-funded research Research Triangle Institute · NIH-10878979

This study is working to make sure that naloxone, a medication that can save lives during an opioid overdose, is more easily available to everyone, especially Black and Latinx people who use syringes, so they can get the help they need when it matters most.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionResearch Triangle Institute NIH-funded
Lab location1 site (Research Triangle Park, United States)
Project IDNIH-10878979 on NIH RePORTER

What this research studies

This research aims to improve the distribution of naloxone, a life-saving medication that can reverse opioid overdoses, through syringe service programs (SSPs) in California. By conducting a randomized controlled trial, the study will evaluate an intervention designed to ensure that naloxone is equitably distributed, particularly to Black and Latinx individuals who inject drugs, who have been shown to receive naloxone less frequently than their White counterparts. The approach involves using the Systems Analysis and Improvement Approach (SAIA-Naloxone) to enhance access and effectiveness of naloxone distribution. The study builds on previous pilot work that demonstrated significant increases in naloxone distribution among marginalized populations.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who inject drugs, particularly those from Black and Latinx communities in California.

Not a fit: Patients who do not inject drugs or are not part of the targeted racial and ethnic groups may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce opioid overdose deaths among underserved populations by ensuring they have better access to naloxone.

How similar studies have performed: Previous pilot studies have shown success with similar interventions, indicating that this approach has the potential for meaningful impact.

Where this research is happening

Research Triangle Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.