Improving wound healing in older adults by targeting cellular aging
Official title: Targeting Senescence to Improve Wound Healing in Aging
Funded at Boston University Medical Campus · NIH-11127644 · Data updated 2026-11-12
This study is looking at how aging cells impact the healing of wounds in older adults, with the hope of finding better ways to help them heal faster and more effectively.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 1, 2023 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $243,000 |
| NIH project number | 5K76AG083300-03 |
| Project ID | NIH-11127644 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are older adults experiencing delayed wound healing or chronic wounds.
✕Less likely to help
Patients who are younger or do not have issues with wound healing may not benefit from this research.
What this research studies
This research investigates how cellular aging affects wound healing in older adults. It focuses on understanding the role of senescent cells, which can both help and hinder the healing process. By studying the differences in wound healing responses between young and aged mice, the research aims to identify ways to enhance the beneficial effects of senescence while minimizing its negative impacts. The ultimate goal is to develop new treatments that can improve wound healing outcomes for older patients.
Why it matters
Potential benefit: If successful, this research could lead to improved wound healing therapies for older adults, reducing the risk of chronic wounds and infections.
How similar studies have gone: Other research has shown promising results in targeting cellular aging to improve healing, suggesting that this approach may be effective.
Where this research is happening
-
Boston University Medical Campus
Boston, United States Active
Researchers
- Principal investigator: Roh, Daniel Sam — Boston University Medical Campus
- Study coordinator: Roh, Daniel Sam
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.