Improving working memory in people with mild cognitive impairment
Enhancing gamma band response to improve working memory in individuals with mild cognitive impairment
This study is exploring a fun way to help people with mild cognitive impairment (MCI) improve their memory and thinking skills by using a technique that trains their brains to be more active in a specific way, which could also help slow down the progression to Alzheimer's disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10814917 on NIH RePORTER |
What this research studies
This research focuses on enhancing gamma band responses in the brain to improve working memory for individuals experiencing mild cognitive impairment (MCI). The approach involves using EEG-neurofeedback, a technique that trains patients to increase their brain's gamma activity, which is crucial for cognitive functions like attention and memory. By targeting these neural responses, the study aims to slow the progression from MCI to Alzheimer's disease and improve daily functioning. Participants will engage in sessions designed to boost their cognitive abilities through real-time feedback on their brain activity.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with mild cognitive impairment.
Not a fit: Patients with advanced Alzheimer's disease or other severe cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new non-invasive treatments that enhance cognitive function and quality of life for individuals with mild cognitive impairment.
How similar studies have performed: Previous studies have shown positive effects of targeting gamma band responses in animal models, suggesting potential for success in human applications.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Singh, Fiza — University of California, San Diego
- Study coordinator: Singh, Fiza
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.