Improving word-finding skills in people with aphasia using different treatment approaches

Optimizing and understanding semantic feature analysis treatment for aphasia: A randomized controlled comparative-effectiveness trial

NIH-funded research Veterans Health Foundation · NIH-10688141

This study is looking at how different ways of thinking about words can help people with aphasia improve their ability to name things, by comparing two groups: one that thinks of lots of details about each word and another that thinks of just a few, all while getting supportive treatment over five weeks.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVeterans Health Foundation NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-10688141 on NIH RePORTER

What this research studies

This research investigates how varying the number of semantic features that individuals with aphasia generate during treatment affects their ability to find words. Participants will be randomly assigned to two groups: one will generate many features for each word, while the other will generate fewer features. Over five weeks, participants will receive intensive treatment and undergo assessments to evaluate their progress in naming pictures. This approach aims to determine which method is more effective in enhancing communication skills for those with aphasia.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with aphasia, particularly those experiencing word-finding difficulties.

Not a fit: Patients who do not have aphasia or those with severe cognitive impairments unrelated to language may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved therapies for individuals with aphasia, enhancing their ability to communicate effectively.

How similar studies have performed: Previous research has shown promise in using semantic feature analysis for aphasia treatment, suggesting that this approach may yield beneficial results.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.