Improving women's health by targeting liver disease during pregnancy
Targeting Nonalcoholic Fatty Liver Disease during the reproductive period to improve women's health outcomes
['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-10858545
This study is looking at how pregnancy can affect liver health in women, especially those at risk for nonalcoholic fatty liver disease (NAFLD) and its more serious form, and it aims to find early signs of these conditions through simple tests during pregnancy to help improve health for moms and their babies.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10858545 on ClinicalTrials.gov |
What this research studies
This research focuses on nonalcoholic fatty liver disease (NAFLD) and its more severe form, nonalcoholic steatohepatitis (NASH), which are significant health concerns for women, particularly during their reproductive years. The study aims to identify women at risk for these conditions through non-invasive testing during pregnancy, a time when many women engage with healthcare services. By screening pregnant individuals, the research seeks to uncover early signs of NAFLD and understand how pregnancy-related metabolic changes may affect liver health. The findings could lead to better management and treatment strategies for women with NAFLD, ultimately improving their health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women, particularly those with a higher risk of developing NAFLD, such as those with a history of obesity or gestational diabetes.
Not a fit: Patients who are not pregnant or those without risk factors for NAFLD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and better management of liver disease in women, significantly improving their long-term health.
How similar studies have performed: Previous studies have successfully identified at-risk populations for NAFLD using similar screening methods, indicating a promising approach.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KUSHNER, TATYANA — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: KUSHNER, TATYANA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.