NIH-funded research R01 grant

Improving weight loss outcomes by treating insomnia in breast cancer survivors

Official title: The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer

Funded at Johns Hopkins University · NIH-10867335 · Data updated 2026-11-12

This study is looking at how improving sleep through therapy can help women who have survived breast cancer lose weight more effectively, making it easier for them to stay healthy and reduce the chance of cancer coming back.

More Breast Cancer research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University
NIH-funded
Lab location1 site (Baltimore, United States)
Project startJuly 1, 2023
Project endJune 30, 2028
Funding year2024
Award (this year)$645,399
NIH project number5R01CA281220-02
Project IDNIH-10867335 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adult women who are breast cancer survivors and are experiencing insomnia and overweight or obesity.

Less likely to help

Patients who are not breast cancer survivors or those who do not have insomnia may not benefit from this research.

What this research studies

This research investigates how treating insomnia can enhance weight loss efforts in women who have survived breast cancer. It focuses on using cognitive-behavioral therapy for insomnia (CBT-I) to improve sleep quality before starting a behavioral weight loss program. By addressing sleep issues, the study aims to help participants achieve more significant and sustained weight loss, which is crucial for reducing the risk of breast cancer recurrence and improving overall health. The approach combines behavioral interventions with a focus on sleep to tackle the challenges faced by breast cancer survivors in managing their weight.

Why it matters

Potential benefit: If successful, this research could lead to more effective weight loss strategies for breast cancer survivors, improving their health outcomes and quality of life.

How similar studies have gone: Previous studies have shown that cognitive-behavioral therapy for insomnia is effective in breast cancer survivors, but this specific approach of combining it with weight loss interventions is novel.

Where this research is happening

  • Johns Hopkins University
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Wilder Coughlin, Janelle — Johns Hopkins University
  • Study coordinator: Wilder Coughlin, Janelle

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.