Improving ways to prevent HIV in babies from mothers

Informing optimal investments along the preconception to postpartum eMTCT continuum

['FUNDING_OTHER'] · UNIVERSITY OF MINNESOTA · NIH-11175503

This project helps countries in sub-Saharan Africa choose the best and most affordable ways to stop HIV from passing from mothers to their babies.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MINNESOTA (nih funded)
Locations1 site (MINNEAPOLIS, UNITED STATES)
Trial IDNIH-11175503 on ClinicalTrials.gov

What this research studies

Even though medicine has greatly reduced HIV transmission from mothers to children, many babies still get infected each year. This project aims to find the most effective and affordable additional strategies to prevent HIV in children, looking at interventions from before pregnancy through breastfeeding. Researchers will use computer modeling to understand which approaches, like better access to birth control or pre-exposure prophylaxis (PrEP), will have the biggest impact. The goal is to guide health policies in sub-Saharan Africa to eliminate mother-to-child HIV transmission.

Who could benefit from this research

Good fit: This project focuses on informing health policies for pregnant and breastfeeding women and their children in sub-Saharan Africa who are at risk of HIV.

Not a fit: Patients not living in sub-Saharan Africa or those not directly impacted by mother-to-child HIV transmission policies would not directly benefit from this specific policy-focused work.

Why it matters

Potential benefit: If successful, this work could lead to better health policies and programs that significantly reduce the number of children born with HIV, especially in sub-Saharan Africa.

How similar studies have performed: Simulation modeling and decision science have successfully guided HIV treatment and prevention strategies in other areas, suggesting this approach is well-established.

Where this research is happening

MINNEAPOLIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.