Improving Walking for People with Peripheral Artery Disease Through Weight Loss and Exercise
ConProject-001
['FUNDING_OTHER'] · NORTHWESTERN UNIVERSITY · NIH-10891377
This project explores if combining a weight loss program with walking exercise can help overweight or obese individuals with peripheral artery disease walk better.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NORTHWESTERN UNIVERSITY (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-10891377 on ClinicalTrials.gov |
What this research studies
Many people with peripheral artery disease (PAD) are also overweight or obese, which can make walking more difficult and lead to faster decline. While walking exercise is a common treatment for PAD, our past observations suggest that adding weight loss might offer even greater benefits. This project will test if a special weight loss program, combined with exercise, can improve walking ability more effectively than exercise alone. The weight loss approach uses group support, mobile technology, remote coaching, and a specific diet plan.
Who could benefit from this research
Good fit: Ideal candidates are individuals with lower extremity peripheral artery disease who are also overweight or obese (BMI over 28 kg/m2).
Not a fit: Patients who are not overweight or obese, or those without peripheral artery disease, would not be the focus of this particular intervention.
Why it matters
Potential benefit: If successful, this approach could offer a new way for overweight or obese patients with PAD to significantly improve their walking ability and overall functional performance.
How similar studies have performed: Previous observational data and a pilot study have shown promising results, indicating that combining weight loss with walking exercise may lead to less functional decline and improved walking performance.
Where this research is happening
CHICAGO, UNITED STATES
- NORTHWESTERN UNIVERSITY — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MCDERMOTT, MARY MCGRAE — NORTHWESTERN UNIVERSITY
- Study coordinator: MCDERMOTT, MARY MCGRAE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.