Improving walking and fitness after stroke using a non-invasive technique
Ischemic Conditioning and Improved Motor Function Post Stroke
['FUNDING_R01'] · MARQUETTE UNIVERSITY · NIH-10650390
This study is looking at how a gentle technique that temporarily limits blood flow to the weaker leg can help stroke survivors walk faster and improve their heart health while they train on a treadmill.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MARQUETTE UNIVERSITY (nih funded) |
| Locations | 1 site (MILWAUKEE, UNITED STATES) |
| Trial ID | NIH-10650390 on ClinicalTrials.gov |
What this research studies
This research investigates the effects of ischemic conditioning (IC), a non-invasive method that temporarily restricts blood flow to the paretic leg, on improving gait speed and cardiovascular fitness in stroke survivors. Participants will engage in treadmill training combined with IC to assess its impact on muscle activation and walking ability. The study will involve a randomized control design with three groups, allowing researchers to compare the effectiveness of IC combined with treadmill training against other methods. The goal is to enhance recovery and reduce long-term disability associated with stroke.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced a stroke and have difficulty with walking and muscle activation in their affected leg.
Not a fit: Patients who have not had a stroke or those with severe comorbid conditions that prevent participation in physical activity may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved mobility and quality of life for stroke survivors.
How similar studies have performed: Previous research has shown positive effects of ischemic conditioning in other populations, but its application in stroke recovery is still being explored.
Where this research is happening
MILWAUKEE, UNITED STATES
- MARQUETTE UNIVERSITY — MILWAUKEE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HYNGSTROM, ALLISON SUZANNE — MARQUETTE UNIVERSITY
- Study coordinator: HYNGSTROM, ALLISON SUZANNE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.