Improving walking ability after stroke using spinal cord stimulation

Locomotor function following transcutaneous electrical spinal cord stimulation in individuals with hemiplegic stroke

NIH-funded research Rehabilitation Institute of Chicago D/b/a Shirley Ryan Abilitylab · NIH-10914656

This study is looking at how a special electrical stimulation on the spine can help people who have had a stroke improve their walking, especially when combined with walking exercises, to see how it affects their movement and mobility.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRehabilitation Institute of Chicago D/b/a Shirley Ryan Abilitylab NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-10914656 on NIH RePORTER

What this research studies

This research investigates how transcutaneous electrical spinal cord stimulation can enhance walking abilities in individuals who have experienced a hemiplegic stroke. By combining this stimulation with gait training, the study aims to understand the underlying mechanisms that may improve motor function. The approach focuses on evaluating spinal cord changes and their impact on walking patterns, which are often impaired after a stroke. Participants will undergo assessments to measure their response to the stimulation and its effects on their mobility.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have suffered a hemiplegic stroke and experience difficulties with walking.

Not a fit: Patients who have not experienced a stroke or those with other neurological conditions unrelated to stroke may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved rehabilitation techniques that enhance walking abilities for stroke survivors.

How similar studies have performed: Previous research has shown promising results with spinal cord stimulation in animal models, but this approach is relatively novel in human stroke rehabilitation.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.