Improving walking ability after leg artery surgery for patients with peripheral artery disease
IMProving mobility After revasCularizaTion in Peripheral Artery Disease: the IMPACT PAD Trial
This study is looking at whether doing exercises at home and taking a supplement called inorganic nitrate can help people with peripheral artery disease walk better after they've had surgery to improve blood flow in their legs, making it easier for them to stay active and feel better overall.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University at Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10885321 on NIH RePORTER |
What this research studies
This research investigates how home-based exercise and inorganic nitrate supplementation can enhance walking performance in patients with peripheral artery disease (PAD) who have undergone lower extremity revascularization. The study aims to determine if these interventions can provide better outcomes compared to surgery alone. By focusing on improving mobility, the research seeks to make exercise more accessible for patients who find supervised programs burdensome. The approach combines clinical procedures with dietary supplementation to potentially improve recovery and quality of life.
Who could benefit from this research
Good fit: Ideal candidates are patients with peripheral artery disease who are undergoing lower extremity revascularization and experience walking impairments.
Not a fit: Patients who do not have peripheral artery disease or those with limb-threatening ischemia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved walking ability and overall mobility for patients recovering from leg artery surgery.
How similar studies have performed: Previous research has shown that combining revascularization with supervised exercise can improve walking performance, suggesting that this home-based approach may also be effective.
Where this research is happening
Chicago, United States
- Northwestern University at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Mcdermott, Mary Mcgrae — Northwestern University at Chicago
- Study coordinator: Mcdermott, Mary Mcgrae
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.