Improving vocal fold repair with a special hydrogel
Augmenting Vocal Fold Repair Using an Optimized Lamina Propria Extracellular Matrix Derived Hydrogel
This study is testing a special gel made from the natural material of vocal folds to help heal voice injuries and improve voice quality for people who have trouble with their voices.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | North Carolina State University Raleigh NIH-funded |
| Lab location | 1 site (Raleigh, United States) |
| Project ID | NIH-10614946 on NIH RePORTER |
What this research studies
This research focuses on developing a hydrogel derived from the extracellular matrix of vocal folds to enhance the repair of vocal fold injuries. The approach involves using a biocompatible material that mimics the natural structure of vocal fold tissue, aiming to restore normal function and improve voice quality. By utilizing minimally invasive techniques, the research seeks to provide a safe and effective treatment option for individuals suffering from voice impairments. The study will assess the hydrogel's ability to promote tissue remodeling and healing in patients with vocal fold scars.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing voice impairments or dysphonia due to vocal fold injuries or scarring.
Not a fit: Patients with voice disorders not related to vocal fold injuries or those with other underlying health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for voice impairments, enhancing communication abilities for millions of affected individuals.
How similar studies have performed: Previous research has shown promising results using extracellular matrix-derived scaffolds for tissue repair, indicating potential success for this novel approach.
Where this research is happening
Raleigh, United States
- North Carolina State University Raleigh — Raleigh, United States (Active)
Researchers
- Principal investigator: Freytes, Donald O — North Carolina State University Raleigh
- Study coordinator: Freytes, Donald O
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.