Improving vitamin D levels and reducing Alzheimer’s risk in African Americans
Optimization of Glutathione Levels and Alzheimer Disease Risk in African Americans
This study is looking at whether boosting vitamin D levels can help lower the risk of Alzheimer’s disease in African Americans, and it will compare the effects of vitamin D alone to vitamin D combined with another supplement to see which is more helpful.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Louisiana State Univ Hsc Shreveport NIH-funded |
| Lab location | 1 site (Shreveport, United States) |
| Project ID | NIH-10475166 on NIH RePORTER |
What this research studies
This research investigates how optimizing vitamin D levels in African Americans can reduce the risk of Alzheimer’s disease. It focuses on the role of glutathione, a key antioxidant, and its relationship with vitamin D levels. The study will conduct a randomized, double-blind, placebo-controlled clinical trial to compare the effects of vitamin D supplementation alone versus vitamin D combined with L-cysteine, a precursor to glutathione. By analyzing blood samples and health outcomes, the research aims to identify effective strategies for improving health disparities in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American individuals who have low levels of vitamin D and are at risk for Alzheimer’s disease.
Not a fit: Patients who already have adequate vitamin D levels or do not have risk factors for Alzheimer’s disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved vitamin D levels and reduced risk of Alzheimer’s disease among African Americans.
How similar studies have performed: Previous studies have shown promising results with vitamin D and glutathione supplementation in improving health outcomes, suggesting potential success for this approach.
Where this research is happening
Shreveport, United States
- Louisiana State Univ Hsc Shreveport — Shreveport, United States (Active)
Researchers
- Principal investigator: Jain, Sushil K — Louisiana State Univ Hsc Shreveport
- Study coordinator: Jain, Sushil K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.