Improving vision for keratoconus patients with advanced contact lenses

Adding Personalized Wavefront-Compensating Optics to a Contact Lens After Lens Manufacture

NIH-funded research University of Houston · NIH-10724501

This study is testing a new type of contact lens designed specifically for people with keratoconus to help improve their vision by using special technology that better corrects the unique distortions caused by their condition.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Houston NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-10724501 on NIH RePORTER

What this research studies

This research focuses on developing a new type of contact lens that incorporates personalized wavefront-compensating optics to better correct vision for individuals with keratoconus, a condition that causes distorted vision due to corneal irregularities. Traditional soft contact lenses are ineffective for this condition, and current rigid lenses do not fully address the higher-order optical aberrations that keratoconus patients experience. By utilizing wavefront-guided correction, this approach aims to provide a more tailored solution that enhances visual outcomes and quality of life for patients. The study will involve testing these advanced lenses to evaluate their effectiveness in improving vision.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with keratoconus who are currently experiencing visual impairment.

Not a fit: Patients with conditions unrelated to keratoconus or those who do not wear contact lenses may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the visual acuity and quality of life for patients suffering from keratoconus.

How similar studies have performed: Previous research has shown promise with wavefront-guided corrections in other types of lenses, but this specific application in soft contact lenses is relatively novel.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Corneal DiseasesCorneal Disordercornea disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.