Improving ventilation techniques for newborns to reduce lung disease

SCH: INT: Smart and Connected Health for Newborn Ventilation

NIH-funded research Drexel University · NIH-10692891

This study is looking at new ways to help newborns, especially those at risk for lung problems, breathe better without needing invasive treatments, using smart technology to monitor their breathing and work with ventilators.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDrexel University NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10692891 on NIH RePORTER

What this research studies

This research focuses on enhancing ventilation methods for newborns, particularly those at risk of bronchopulmonary dysplasia (BPD), a common chronic lung disease. The project aims to develop a smart health solution that monitors newborns non-invasively and synchronizes their breathing with ventilators, potentially reducing the need for invasive procedures. By utilizing advanced algorithms and non-invasive ventilation techniques, the research seeks to improve outcomes for preterm infants who require respiratory support. The approach includes the use of nasal intermittent positive pressure ventilation (NIPPV) and aims to create a control loop for better management of ventilation.

Who could benefit from this research

Good fit: Ideal candidates for this research are preterm infants who require mechanical ventilation and are at risk for developing bronchopulmonary dysplasia.

Not a fit: Patients who are not preterm or do not require respiratory support may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the incidence of chronic lung disease in newborns and improve their long-term health outcomes.

How similar studies have performed: Previous studies have shown promising short-term benefits of non-invasive ventilation techniques, indicating potential for success in this innovative approach.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions chronic lung disease in infantschronic lung disease in neonatal infantschronic lung disease in neonateschronic lung disease in newbornschronic lung disease in prematurity
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.