Improving ventilation techniques during pediatric cardiac arrest
Official title: OPTImal VENTilation to Improve Pediatric Cardiac Arrest Outcomes
Funded at Children's Hosp of Philadelphia · NIH-11047199 · Data updated 2026-11-12
This study is looking at how to make CPR better for kids who have heart problems, by teaching doctors and nurses the best ways to help them breathe during emergencies, so they can survive and recover more effectively.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | January 20, 2025 |
| Project end | December 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $866,579 |
| NIH project number | 1R01HD114622-01A1 |
| Project ID | NIH-11047199 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years who experience cardiac arrest, particularly those with underlying respiratory conditions.
✕Less likely to help
Patients who are older than 11 years or those who do not experience cardiac arrest may not benefit from this research.
What this research studies
This research focuses on enhancing the effectiveness of cardiopulmonary resuscitation (CPR) for children experiencing cardiac arrest. It investigates the optimal ventilation strategies, particularly in light of the American Heart Association's updated recommendations for ventilation rates. The study will implement a training program for healthcare providers using a bundle of educational tools and real-time guidance to ensure compliance with these ventilation rates. By conducting a hybrid cluster-randomized trial, the research aims to assess whether these improved techniques can lead to better survival outcomes for pediatric patients.
Why it matters
Potential benefit: If successful, this research could significantly increase survival rates for children who suffer cardiac arrest by optimizing CPR ventilation techniques.
How similar studies have gone: Previous research has shown that improved training and adherence to updated CPR guidelines can enhance patient outcomes, indicating a promising avenue for this approach.
Where this research is happening
-
Children's Hosp of Philadelphia
Philadelphia, United States Active
Researchers
- Principal investigator: Sutton, Robert Michael — Children's Hosp of Philadelphia
- Study coordinator: Sutton, Robert Michael
Related research
Other NIH-funded projects on the same topics.
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Multi-center study on how ventilation during CPR relates to cardiac arrest outcomes
A large, real-world study will look at how ventilation during CPR affects survival after out-of-hospital cardiac arrest in adults.
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Specialized post-arrest care after cardiac arrest
A large, nationwide effort tests whether transferring cardiac arrest patients to a specialized post-arrest care center improves recovery compared with usual care.
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Reduce bias in predicting brain recovery after cardiac arrest
This project aims to make brain-recovery predictions more accurate for people who survive cardiac arrest by comparing outcomes between the United States and Brazil.
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Fairer brain recovery predictions after cardiac arrest through U.S.–Brazil collaboration
This project aims to find better ways to predict brain recovery for people who survive cardiac arrest but have possible brain injury.
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Improving predictions of brain recovery after cardiac arrest
This project compares outcomes after cardiac arrest in the U.S. and Brazil to learn which tests best predict who will regain brain function for people who survive cardiac arrest.
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Reducing biased predictions of brain recovery after cardiac arrest
This project looks at cardiac arrest survivors in the US and Brazil to find more accurate ways to predict brain recovery and avoid premature stopping of life support.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.