Improving vaginal health for transgender men on testosterone

Assessing and Promoting Vaginal Health for Transgender Men on Testosterone: A Mixed Methods Study

['FUNDING_OTHER'] · UNIVERSITY OF ALABAMA AT BIRMINGHAM · NIH-10947965

This study is looking at how testosterone therapy affects the vaginal health of transgender men, with the goal of finding ways to improve their sexual health and healthcare experiences.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF ALABAMA AT BIRMINGHAM (nih funded)
Locations1 site (BIRMINGHAM, UNITED STATES)
Trial IDNIH-10947965 on ClinicalTrials.gov

What this research studies

This research focuses on understanding and enhancing the vaginal health of transgender men who are undergoing testosterone therapy. It aims to identify the negative effects of testosterone on vaginal health, such as thinning of the vaginal lining and increased risk of infections. By using a mixed methods approach, the study will gather both qualitative and quantitative data to better assess and address the unique sexual health needs of this underserved population. The goal is to develop community-informed strategies that improve healthcare experiences and outcomes for transgender men.

Who could benefit from this research

Good fit: Ideal candidates for this research are transgender men aged 21 and older who are currently on testosterone therapy.

Not a fit: Patients who have undergone bottom surgery and no longer have a vagina may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved sexual health services and outcomes for transgender men, reducing health disparities in this population.

How similar studies have performed: While research on transgender health is growing, this specific focus on vaginal health in transgender men is relatively novel and has not been extensively studied.

Where this research is happening

BIRMINGHAM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.