Improving urine drug testing for opioid use disorder treatment.
Official title: Establishing an Evidence Base to Increase the Utility of Urine Drug Testing in Opioid Use Disorder Treatment.
Funded at Johns Hopkins University · NIH-11116859 · Data updated 2026-11-12
This study is looking at how urine drug testing is used in treating people with opioid use disorder to find better ways to help them get the care they need.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | June 15, 2024 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $683,336 |
| NIH project number | 5R01DA059528-02 |
| Project ID | NIH-11116859 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with opioid use disorder who are undergoing treatment.
✕Less likely to help
Patients who do not have opioid use disorder or are not receiving treatment for it may not benefit from this research.
What this research studies
This research aims to enhance the effectiveness of urine drug testing (UDT) in the treatment of opioid use disorder (OUD). It will analyze how UDT is currently used across different patients and healthcare providers, identifying variations and inconsistencies in testing practices. By examining a large national database, the study will explore factors that influence UDT application and its impact on patient care. The goal is to develop evidence-based guidelines that can improve treatment outcomes for individuals with OUD.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for patients with opioid use disorder.
How similar studies have gone: Previous research has shown that improving testing protocols can enhance treatment outcomes in addiction care, suggesting potential success for this approach.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Kennedy Hendricks, Alene — Johns Hopkins University
- Study coordinator: Kennedy Hendricks, Alene
Related research
Other NIH-funded projects on the same topics.
-
Systems analysis to improve opioid use disorder care after jail release (SAIA-MOUD)
A program to help people with opioid use disorder get better, faster, and safer care after they leave jail.
-
Precise epigenetic drugs for opioid addiction
A tiny, targeted drug approach is being developed to help people with opioid use disorder by rewriting the epigenetic signals in the brain to reduce cravings and relapse risk.
-
Increasing Access to Medications for Opioid Use Disorder for Unhoused Montanans
This project helps unhoused people in Montana get life-saving medicines for opioid use disorder through clinics connected to syringe service programs, a nurse-led MOUD model, and peer support.
-
Optimizing long-acting PrEP and opioid treatment for people in jails and prisons
This project tests a real-world approach to using long-acting PrEP and buprenorphine for HIV prevention and opioid treatment among incarcerated individuals and after release.
-
Scaling up medications for opioid use disorder in residential treatment programs
This grant studies how to help residential treatment programs provide medications for opioid use disorder to reduce overdoses after discharge, focusing on real-world settings and policies.
-
Increasing Capacity at a Native Community Clinic to Improve Opioid Care for urban AI/AN
This grant helps a Native American health clinic build its research capacity to better serve urban American Indian and Alaska Native people dealing with opioid use disorder and related health issues.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.