Improving understanding of orofacial clefts in children
Enhanced Data from Orofacial Cleft Trios to Strengthen the Gabriella Miller Kids First (GMKF) Discovery Goals
['FUNDING_R03'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10599333
This study is looking at orofacial clefts, which are common birth defects affecting the lip and palate, to gather more information about their causes and effects, so that families with children who have these conditions can get better support and treatment.
Quick facts
| Phase | ['FUNDING_R03'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-10599333 on ClinicalTrials.gov |
What this research studies
This research focuses on nonsyndromic orofacial clefts, which are common birth defects affecting the lip and palate. It aims to enhance genetic and phenotype data from families with affected children to better understand the causes and impacts of these conditions. By analyzing genetic information and health outcomes, the research seeks to identify risk factors and improve treatment strategies for affected individuals. Patients may benefit from improved interventions and support based on the findings.
Who could benefit from this research
Good fit: Ideal candidates for this research include children diagnosed with nonsyndromic orofacial clefts and their families.
Not a fit: Patients with syndromic orofacial clefts or those without a family history of the condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatment options and support for children with orofacial clefts.
How similar studies have performed: Previous research has successfully utilized genetic data to understand orofacial clefts, indicating a promising approach for this study.
Where this research is happening
PITTSBURGH, UNITED STATES
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MARAZITA, MARY L. — UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- Study coordinator: MARAZITA, MARY L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.