NIH-funded research R21 grant

Improving understanding of factors influencing adolescent substance use

Official title: Improving Causal Inference for National Adolescent Substance Use Datasets

Funded at Purdue University · NIH-11110496 · Data updated 2026-11-12

This study is looking at how things like parental supervision can affect substance use in teenagers, and it's designed to help improve ways to prevent harmful behaviors in young people.

More Substance Use research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionPurdue University
NIH-funded
Lab location1 site (West Lafayette, United States)
Project startJune 15, 2024
Project endMay 31, 2026
Funding year2025
Award (this year)$196,250
NIH project number5R21DA059778-02
Project IDNIH-11110496 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adolescents aged 12-20 who may be at risk for substance use or are currently experiencing substance use issues.

Less likely to help

Patients outside the age range of 0-20 years or those not involved in substance use behaviors may not benefit from this research.

What this research studies

This research aims to enhance the understanding of adolescent substance use by developing advanced statistical methods to analyze data from the Adolescent Brain and Cognitive Development study. It focuses on identifying causal factors, particularly parental monitoring, that may influence substance use behaviors in adolescents. By comparing new models with existing ones, the research seeks to refine intervention strategies to prevent harmful substance use among youth. The study will also conduct simulations to determine the necessary sample sizes for effective analysis.

Why it matters

Potential benefit: If successful, this research could lead to more effective prevention strategies for adolescent substance use, ultimately improving youth health outcomes.

How similar studies have gone: Previous research has shown success in using longitudinal data to inform interventions for adolescent substance use, making this approach both relevant and promising.

Where this research is happening

  • Purdue University
    West Lafayette, United States
    Active

Researchers

  • Principal investigator: Marceau, Kristine — Purdue University
  • Study coordinator: Marceau, Kristine

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.